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Neither B cell nor T cell – the unique group of innate lymphoid cells

This special issue of Biomedical Journal contains four review articles that analyze the development and biology of innate lymphoid cells (ILCs), which are the most recently-discovered subsets of innate immune cells. This unique group of lymphoid cells lacks the RAG gene and consequently does not express B cell nor T cell antigen-specific receptors. They are abundant at mucosal surfaces, where they play a role in immunity and homeostasis. The ILCs are the focus of intensive research efforts to understand their development and function.

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