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New findings suggest organ tissues become increasingly immune throughout life

Researchers have offered new ways to think about the immune system thanks to a recent study published in Nature. Their research, which indicates organ tissues become increasingly immune throughout life, may begin to alter fundamental ideas regarding the rules of vaccination and the immune system's function within the body.


The study's major findings, include:

  • Antiviral T cells that reside in most organs of the body persist over time and in the face of extensive infectious exposures;

  • Unlike other organ systems, the immune system becomes increasingly immune throughout life, which is a natural response to accumulated microbial exposures over time;

  • Up to 25% of the cells in organs were immune cells, indicating that the immune system significantly contributes to the cellular makeup of the body;

  • And, along with antiviral T cells, most other immune cells are durably tissue-resident in organs as well.



https://medicalxpress.com/news/2021-04-tissues-increasingly-immune-life.html

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