Verrucarin A, a secondary metabolite produced by the #fungus Myrothecium spp, reduced the amounts of amyloid-beta in reprogrammed cortical neurons. #mycology #Alzheimers #Alzheimer #dementia Eating well, exercising regularly, and having a satisfying social life are all crucial to staying healthy. Sometimes, however, it can be the tiniest things that make the biggest difference. In this case, those tiny things are microorganisms, such as bacteria and fungi. The metabolites the

#saliva #neurology #dementia #Alzheimers #diagnosis Current research efforts on neurological diseases are focused on identifying novel disease biomarkers to aid in diagnosis, provide accurate prognostic information and monitor disease progression. With advances in detection and quantification methods in genomics, proteomics and metabolomics, saliva has emerged as a good source of samples for detection of disease biomarkers. Obtaining a sample of saliva offers multiple advanta

#oralhealth #inflammation #Alzheimers #pregnancy #pneumonia #obesity #diabetes #heartidisease A growing body of literature suggests that there is a link between periodontitis and systemic diseases. These diseases include cardiovascular disease, gastrointestinal and colorectal cancer, diabetes and insulin resistance, and Alzheimer's disease, as well as respiratory tract infection and adverse pregnancy outcomes. The presence of periodontal pathogens and their metabolic by-produ

#Alzheimers #microbiota #microbiome #oralhealth #dental #dentistry #oral #heart A growing body of literature suggests that there is a link between #periodontitis and systemic diseases. These diseases include #cardiovascular disease, gastrointestinal and #colorectal cancer, #diabetes and insulin resistance, and Alzheimer's disease, as well as respiratory tract infection and adverse pregnancy outcomes. The presence of #periodontal pathogens and their metabolic by-products in th

A growing body of literature suggests that there is a link between periodontitis and systemic diseases. These diseases include cardiovascular disease, gastrointestinal and colorectal cancer, diabetes and insulin resistance, and Alzheimer's disease, as well as respiratory tract infection and adverse pregnancy outcomes. The presence of periodontal pathogens and their metabolic by-products in the mouth may in fact modulate the immune response beyond the oral cavity, thus promoti

Coronary heart disease and stroke are the two leading causes of death for Homo sapiens on planet Earth, according to a new report from the World Health Organization. This fact has remained unchanged for the past two decades. But this analysis of global deaths over the past 20 years finds significant shifts in how people die — as well as dramatic differences in what leads to death in different regions. Noncommunicable diseases such as dementia and diabetes are now claiming mor