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MOSTLY MICROBES AND INFECTIOUS DISEASES

Welcome to Mostly Microbes and Infectious Diseases. David Ojcius posts newspaper and journal articles in the broad field of microbiology.

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Making it easier to be a patient in times of a pandemic

by David Chambers, Michelle Brady, David Ojcius, Evelyn Cuny #COVID19 #COVID #SARSCoV2 #coronavirus #dentistry #dental 1 PROBLEM What responses are needed when a public health crisis, the COVID-19 pandemic, disrupts continuity of care in a dental school clinic? To what extent do fears regarding safety during treatment deter patients from attending appointments in dental school clinics and can the school control these factors to ensure educational experiences? Much attention h

Dental Care is Essential Care: The Importance of Getting Back on Track with Your Oral Healthcare

#dentalcare #oralhealth #dentistry #dental #pandemic #COVID19 Over the past year and a half, many of us have taken “business casual” to new lengths, working in sweatpants or pajamas and forgoing many of our usual self-care routines. While we lamented closed shops and salons, many of us also glossed over missed appointments with our physicians and —our dentists. The COVID-19 pandemic may have placed a spotlight on health, however physical restrictions resulted in missed dental

Tooth Loss May Affect Ability to Carry Out Everyday Tasks

#oralhealth #teeth #tooth #dental #dentistry #dentist Summary: Older adults with more natural teeth are better able to carry out simple everyday tasks like cooking and cleaning compared to those who have lost their teeth, a new study reports. Researchers found a causal link between tooth loss and functional capacity in older adults. Tooth loss was also associated with a decline in social activity. The study published in the Journal of American Geriatrics Society, analysed dat

The Role of Medicine and Technology in Shaping the Future of Oral Health

by Namrata Nayyar, David Ojcius, Arthur Dugoni #oralhealth #dental #dentistry #technology #medicine #genomics #robotics #artificialintelligence #AI This commentary describes the changes taking place in dentistry and speculates on improvements that could happen soon. Advances in health care will have an impact on the integration and delivery of oral care; conversely, there is growing acceptance that oral health impacts systemic health. Technological innovations are changing th

Involvement of inflammasomes in immune response against infection by periodontal bacteria

by Kívia Queiroz De Andrade, Cássio Luiz Coutinho Almeida-da-Silva, David Ojcius, Robson Coutinho-Silva #inflammation #immunology #microbiology #oralhealth #dental #dentistry #periodontal #oral Differential involvement of the canonical and noncanonical inflammasomes in the immune response against infection by the periodontal bacteria Porphyromonas gingivalis and Fusobacterium nucleatum We examined the involvement of the P2 × 7 receptor and the canonical and noncanonical infla

Is there an association between oral health and severity of COVID-19 complications?

by Nathalie Botros, Parvati Iyer, David Ojcius #oralhealth #COVID19 #coronavirus #dental #dentistry Most patients with severe complications from COVID-19 have underlying conditions such as obesity, diabetes, and hypertension. In parallel, there is growing evidence for a link between periodontitis and non-oral systemic diseases. The oral cavity is also a reservoir for respiratory pathogens, and patients with periodontal disease are more likely to develop hospital-acquired pneu

Involvement of canonical and noncanonical inflammasomes in immune response against oral pathogens

#immunology #oralhealth #innateimmunity #inflammation #inflammasome #dental #dentistry We examined the involvement of the P2 × 7 receptor and the canonical and noncanonical inflammasomes in the control of single-species or dual-species infection by the periodontal bacteria Porphyromonas gingivalis and Fusobacterium nucleatum in cells and mice. Stimulation of the P2 × 7 receptor leads to activation of the canonical NLRP3 inflammasome and activation of caspase-1, which leads to

Nathalie Botros, Parvati Iyer, David Ojcius: Does oral health affect severity of COVID-19?

#COVID19 #coronavirus #oralhealth #dental #dentistry Most patients with severe complications from COVID-19 have underlying conditions such as obesity, diabetes, and hypertension. In parallel, there is growing evidence for a link between periodontitis and non-oral systemic diseases. The oral cavity is also a reservoir for respiratory pathogens, and patients with periodontal disease are more likely to develop hospital-acquired pneumonia than healthy individuals. We therefore hy

Need a New Tooth? Drug Discovered to Regenerate Lost Teeth

#oralhealth #dental #dentistry #dentist Need a New #Tooth? Drug Discovered to Regenerate Lost #Teeth A new study reports that an antibody for one gene (uterine sensitization associated gene-1 or USAG-1) can stimulate tooth growth in mice suffering from tooth agenesis, a congenital condition. https://scitechdaily.com/need-a-new-tooth-drug-discovered-to-regenerate-lost-teeth/

Involvement of inflammasomes in the immune response against infection by the periodontal bacteria

#immunology #inflammation #innateimmunity #oralhealth #dental #dentistry We examined the involvement of the P2 × 7 receptor and the canonical and noncanonical inflammasomes in the control of single-species or dual-species infection by the periodontal bacteria Porphyromonas gingivalis and Fusobacterium nucleatum in cells and mice. Stimulation of the P2 × 7 receptor leads to activation of the canonical NLRP3 inflammasome and activation of caspase-1, which leads to cleavage of p

Association between periodontal pathogens and systemic disease

#Alzheimers #microbiota #microbiome #oralhealth #dental #dentistry #oral #heart A growing body of literature suggests that there is a link between #periodontitis and systemic diseases. These diseases include #cardiovascular disease, gastrointestinal and #colorectal cancer, #diabetes and insulin resistance, and Alzheimer's disease, as well as respiratory tract infection and adverse pregnancy outcomes. The presence of #periodontal pathogens and their metabolic by-products in th

Making it easier to be a patient in times of a pandemic

What responses are needed when a public health crisis, the #COVID19 #pandemic, disrupts continuity of care in a #dental school clinic? To what extent do fears regarding safety during treatment deter patients from attending appointments in dental school clinics and can the school control these factors to ensure educational experiences? #dentistry https://onlinelibrary.wiley.com/doi/full/10.1002/jdd.12588

Microbes’ matchmaker helps bacteria to slime your teeth

Scientists studied biofilm formation by Streptococcus mutans, one of the main causes of tooth decay. They found that S. mutans has a genetic complex that promotes the formation of robust biofilms, and identified five molecules that this complex encodes. #biofilms #microbiology #caries #oralhealth #dentistry #dental https://www.nature.com/articles/d41586-021-00619-6

Less drilling, less germ spray: Dentistry adapts to the Covid era.

Drills & other equipment used by dentists can produce suspended droplets or aerosols, potentially carrying the #coronavirus, which could endanger patients & staff. As a result, #dental offices operate in a markedly different way than before the #COVID19 pandemic. #dentistry #oralhealth https://www.nytimes.com/2021/02/13/world/less-drilling-less-germ-spray-dentistry-adapts-to-the-covid-era.html

The Role of Medicine & Technology in Shaping the Future of Oral Health.

This commentary describes the changes taking place in #dentistry and speculates on improvements that could happen soon. Advances in health care will have an impact on the integration and delivery of oral care; conversely, there is growing acceptance that #oralhealth impacts systemic health. Technological innovations are changing the face of medical care and are quickly becoming integrated into dentistry. Advances in novel antimicrobials, #genomics, #robotics and #artificialin

Association between periodontal pathogens and systemic disease

A growing body of literature suggests that there is a link between periodontitis and systemic diseases. These diseases include cardiovascular disease, gastrointestinal and colorectal cancer, diabetes and insulin resistance, and Alzheimer's disease, as well as respiratory tract infection and adverse pregnancy outcomes. The presence of periodontal pathogens and their metabolic by-products in the mouth may in fact modulate the immune response beyond the oral cavity, thus promoti

On Lifelong Learning as a Researcher

About life of university professors: "The industry I’m in is actually two in one: teaching and research. I love teaching and interacting with students. In many ways I learn as I teach them. I love their enthusiasm and their optimism. The thing about research is you are a student for life. You constantly have to learn new skills. It requires you to be a lifelong learner, which is something I enjoy." #LifelongLearning #Research #university #dental #education https://thrivegloba

Association Between Oral Health & Systemic Disease.

Recent research shows a link between health conditions such as diabetes, cardiovascular disease & periodontal disease. But it's still unknown how oral bacteria can have such an impact on systemic health. #oralhealth #medicine #dentistry #dental https://www.trueactivist.com/david-ojcius-discusses-the-association-between-oral-health-and-systemic-disease/

The Role of Medicine and Technology in Shaping the Future of Oral Health

This commentary in the California Dental Association Journal describes the changes taking place in dentistry and speculates on improvements that could happen soon. Advances in health care will have an impact on the integration and delivery of oral care; conversely, there is growing acceptance that oral health impacts systemic health. Technological innovations are changing the face of medical care and are quickly becoming integrated into dentistry. Advances in novel antimicrob

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