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MOSTLY MICROBES AND INFECTIOUS DISEASES
Welcome to Mostly Microbes and Infectious Diseases. David Ojcius posts newspaper and journal articles in the broad field of microbiology.

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David Ojcius
Jun 30, 20231 min read
Parabacteroides distasonis uses dietary inulin to suppress NASH via pentadecanoic acid
Study shows that gut #microbiota members can use dietary fibre to generate beneficial metabolites to suppress metabolic disease....
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David Ojcius
Jun 26, 20233 min read
Pacific has one of most successful years for grants in school history
University of the Pacific secured 62 grants from federal, state and county agencies totaling more than $36 million—one of the best years...
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David Ojcius
Jun 24, 20233 min read
Hunter-gatherer lifestyle fosters thriving gut microbiome
Sequencing the #microbiome of hunter-gatherers & city-dwellers shows that Western lifestyle decreases diversity of gut-bacteria...
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David Ojcius
Jun 18, 20233 min read
Researchers uncover a cellular process that leads to inflammation
Cedars-Sinai investigators have identified several steps in a cellular process responsible for triggering one of the body's important...
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David Ojcius
Jun 14, 20234 min read
Negative Regulatory NLRs Mitigate Inflammation via NF-κB Pathway in Inflammatory Bowel Disease
A subset of NLRs function to mitigate overzealous pro-inflammatory signaling produced by NF-κB activation. Under normal pathophysiologic...
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David Ojcius
Jun 8, 20233 min read
Taurine deficiency as a driver of aging
Studying various animals, a study found that the amount of the semi-essential amino acid #taurine in circulation decreased with age....
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David Ojcius
Jun 3, 20237 min read
Microbiota and Nod-like receptors balance inflammation and metabolism during obesity and diabetes
Gut #microbiota influence host immunity and metabolism during obesity. Bacterial sensors of the innate immune system relay signals from...
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David Ojcius
May 28, 20234 min read
In China (and elsewhere), an Unseen & Dangerous Foe Takes Root: Lethal Fungi.
Rising temperatures & ecosystem disturbances are creating a hotbed for fungi that can spark hard-to-treat infections in peoples’ lungs,...
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David Ojcius
May 25, 20231 min read
Oral Microbiome and Health
Guest editors: Ozlem Yilmaz and David Ojcius. There is growing awareness that microbes in the oral cavity have a large effect on both...
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David Ojcius
May 15, 20231 min read
Centenarians have diverse gut virome w/ potential to modulate metabolism & promote healthy lifespan
Compared with viromes of young adults (>18 yr) & old people (>60 yr), centenarians have diverse #virome including previously undescribed...
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David Ojcius
May 13, 20231 min read
The oral microbiota: living with a permanent guest
by Maria Avila, David M Ojcius, Ozlem Yilmaz. The oral cavity of healthy individuals contains hundreds of different bacterial, viral, and...
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David Ojcius
May 7, 20232 min read
Infection of the oral cavity with SARS-CoV-2 variants: Scope of salivary diagnostics
Coronaviruses, including #SARSCoV2, have caused pandemics in the past two decades. The most prevalent SARS-CoV-2 variants of concern can...
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David Ojcius
May 6, 20231 min read
David Ojcius Discusses The Association Between Oral Health And Systemic Disease
David Ojcius is the assistant dean of research and the chair of the Biomedical Sciences department at the University of the Pacific....
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David Ojcius
Apr 30, 20231 min read
Dicer regulates activation of the NLRP3 inflammasome
by David M. Ojcius, Ardavan Jafari, Laxmi Yeruva, Christian W. Schindler, Ali A. Abdul-Sater Inflammation plays a critical role in...
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David Ojcius
Apr 13, 20232 min read
What SuperAgers show us about longevity, cognitive health as we age
· Eat like a centenarian by incorporating fiber-rich foods into your diet. · Exercise your body. · #Exercise your brain. · Stay...
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David Ojcius
Apr 12, 20233 min read
Longevity of centenarians is reflected by the gut microbiome with youth-associated signatures
Centenarians display youth-associated features in gut #microbiome such as over-representation of #Bacteroides-dominated enterotype,...
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David Ojcius
Apr 8, 20233 min read
Intermittent fasting modulates gut microbiota and improves obesity and host energy metabolism
A small study in humans found that #IntermittentFasting modulates the intestinal #microbiota & improves #obesity & host energy...
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David Ojcius
Mar 30, 20235 min read
Beta lactamase-producing Neisseria gonorrhoeae alleviates Amoxicillin-induced chlamydial persistence
Highlights • #Chlamydia trachomatis (CT) and $Neisseria gonorrhoeae (NG) co-infections are common. • N. gonorrhoeae may cause a...
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David Ojcius
Mar 28, 20235 min read
Probiotic supplements may do the opposite of boosting your gut health
In healthy people, #probiotic supplements offer little benefit & can potentially do more harm than good. Studies show that taking...
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David Ojcius
Mar 26, 20232 min read
Mucin glycans drive oral microbial community composition & function
Study found mucins shape oral #microbiota by serving as nutrients to support metabolic diversity, organizing spatial structure thru...
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