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MOSTLY MICROBES AND INFECTIOUS DISEASES
Welcome to Mostly Microbes and Infectious Diseases. David Ojcius posts newspaper and journal articles in the broad field of microbiology.

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Calorie restriction in humans builds strong muscle & stimulates healthy aging genes
#CalorieRestriction is known to delay progression of age-related diseases in animal models. A new study suggests the same biological...
David Ojcius
Oct 14, 20232 min read


Scientists Use CRISPR to Make Chickens More Resistant to Bird Flu
Scientists have used #CRISPR to create chickens that have some resistance to #avianflu. The research is "proof of concept that we can...
David Ojcius
Oct 11, 20233 min read


Urbanization associates with restricted gut microbiome diversity and delayed maturation in infants
Urbanization associates with restricted gut #microbiome diversity & delayed maturation in infants in Senegal. •Urban infants also more...
David Ojcius
Oct 9, 20231 min read


Gut barrier disruption and chronic disease
by Jan Martel, Shih-Hsin Chang, Yun-Fei Ko, Tsong-Long Hwang, John D. Young & David M. Ojcius Maintenance of gut barrier integrity is...
David Ojcius
Oct 4, 20233 min read


Jorvik: a membrane-containing phage that will likely found a new family within Vinavirales
Study identifies a new type of membrane-containing #bacteriophage, Jorvik, that infects the freshwater mixotrophic model bacterium...
David Ojcius
Sep 30, 20231 min read


Your microbes live on after you die − how your necrobiome recycles your body to nourish new life
How your #necrobiome recycles your body to nourish new life. Studies show that not only do our microbes continue to live on after we die,...
David Ojcius
Sep 29, 20234 min read


How climate change could make fungal diseases worse
Fungal diseases in general are appearing in places they have never been seen before & previously harmless or mildly harmful #fungi are...
David Ojcius
Sep 27, 20232 min read


Pacific has one of most successful years for grants in school history
University of the Pacific secured 62 grants from federal, state and county agencies totaling more than $36 million—one of the best years...
David Ojcius
Sep 20, 20233 min read


Inflammasome-mediated glucose limitation induces antibiotic tolerance in Staphylococcus aureus
• #Staphylococcus aureus activates #NLRP3 #inflammasome in macrophages • NLRP3 activation --> depletion of glucose in macrophage...
David Ojcius
Sep 16, 20231 min read


The oral microbiome: diversity, biogeography and human health
Review article highlights recent understanding of biogeography of oral niches at the species level & summarizes the relationship between...
David Ojcius
Sep 12, 20233 min read
More reasons to eat mushrooms & fried crickets!
Study in mice found that digesting #chitin, an abundant dietary fiber in insect exoskeletons & mushrooms & crustacean shells, engages the...
David Ojcius
Sep 9, 20232 min read


A GWAS in the pandemic epicenter highlights severe COVID-19 risk locus introgressed by Neanderthals
Large GWAS indicated that genetic factors influence the response to #SARSCoV2. However, sex, age, concomitant diseases, differences in...
David Ojcius
Sep 3, 20231 min read


How a simple mouth rinse may be able to predict heart disease risk
Study shows that a simple mouth rinse that checks white blood cell levels may be helpful in predicting #heart disease. The rinse can...
David Ojcius
Aug 20, 20232 min read


Chlamydia and apoptosis: life and death decisions of an intracellular pathogen
The chlamydiae are important obligate intracellular prokaryotic pathogens that, each year, are responsible for millions of human...
David Ojcius
Aug 14, 20232 min read


Cigarette smoking exposure disrupts the regenerative potential of dental pulp stem cells
Introduction: #Smoking is known to alter the regenerative and immunomodulatory properties of many types of mesenchymal stem cells (MSCs)....
David Ojcius
Aug 4, 20233 min read


”We’re All Asgardians”: Scientists Discover New Clues About the Origin of Complex Life
According to newest study, all complex life forms (eukaryotes) trace their roots back to a common ancestor among a group of microbes...
David Ojcius
Aug 2, 20232 min read


Weaker immune response in children with mitochondrial disorders
Researchers find that altered B cell function in children with mitochondrial disorders leads to a weaker & less diverse antibody response...
David Ojcius
Jul 8, 20231 min read


Senolytics combat COVID-19 in aging
#aging increases vulnerability to respiratory viral infections, including by #SARSCoV2. Delval et al. established a causal role for...
David Ojcius
Jul 7, 20234 min read


Parabacteroides distasonis uses dietary inulin to suppress NASH via pentadecanoic acid
Study shows that gut #microbiota members can use dietary fibre to generate beneficial metabolites to suppress metabolic disease....
David Ojcius
Jun 30, 20231 min read


Pacific has one of most successful years for grants in school history
University of the Pacific secured 62 grants from federal, state and county agencies totaling more than $36 million—one of the best years...
David Ojcius
Jun 26, 20233 min read
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