Development of T cell antigen-based human coronavirus vaccines against nAb-escaping SARS-CoV-2 variants
Currently approved vaccines have been successful in preventing the severity of #COVID19 and hospitalization. These vaccines primarily...
Welcome to Mostly Microbes and Infectious Diseases. David Ojcius posts newspaper and journal articles in the broad field of microbiology.
Currently approved vaccines have been successful in preventing the severity of #COVID19 and hospitalization. These vaccines primarily...
Abstract The unceasing global spread of severe acute respiratory syndrome #coronavirus 2 (#SARSCoV2) calls for the development of novel...
Large GWAS indicated that genetic factors influence the response to #SARSCoV2. However, sex, age, concomitant diseases, differences in...
#aging increases vulnerability to respiratory viral infections, including by #SARSCoV2. Delval et al. established a causal role for...
The pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (#SARSCoV2) is receiving worldwide attention, due to the severity...
Coronaviruses, including #SARSCoV2, have caused pandemics in the past two decades. The most prevalent SARS-CoV-2 variants of concern can...
#SARSCoV2-induced #anorexia triggers systemic metabolic alterations. A new study shows that the ketone body β-hydroxybutyrate (BHB)...
As #omicron-specific boosters near, scientists debate how ‘original antigenic sin’ will influence immune responses. In the beginning,...
Just 10 months after the initial genome sequencing of the #SARSCoV2 virus, two mRNA vaccines were demonstrated to provide 95% efficacy...
As #COVID19 death rate globally has fallen, it may be tempting to conclude that #coronavirus is becoming milder. But this not a given. A...
Researchers have developed a rapid T-cell test (the dqTACT assay) that measures the activation of T cells in response to #COVID19. The...
Smell disruption from #COVID19 is becoming less-common, but millions of people still have problems with their sense of #smell. The...
Haven't had #COVID19 yet? It could be more than just luck. Simplest explanation: you have never come into contact with the virus....
After briefly dropping in early months of the #COVID19 pandemic in 2020, rates of sexually transmitted infections in US then resurged...
Two studies show that immune cells infected with #SARSCoV2 can stimulate a large inflammatory response via #inflammasome activation. In...
A #COVID19 outbreak is ravaging a hospital for older adults in Shanghai, China. Workers said that deaths are increasing & resources are...
A surge in people with discolored toes does not seem to be linked to #COVID19. New report suggests that #COVID toe could have been caused...
China has revised the country’s pandemic guidelines to include the use of antiviral pills made by Pfizer, #Paxlovid, as the country...
Europe thought it was done with #COVID19. The UK's daily case rate is still < 1/3 of what it was during the #Omicron peak, but cases are...
Even a mild case of #COVID19 can damage the brain, leading to shrinkage equivalent to up to a decade of #aging, according to a new study....