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MOSTLY MICROBES AND INFECTIOUS DISEASES
Welcome to Mostly Microbes and Infectious Diseases. David Ojcius posts newspaper and journal articles in the broad field of microbiology.

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Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy
Highlights • Exercise-induced microbial formate enhances immune checkpoint inhibitor efficacy • Microbiota-derived formate is essential...
David Ojcius
10 hours ago1 min read
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Biological Functions of Extracellular Vesicles from Mammalian Cells
#ExtracellularVesicles (EVs) are enclosed by a phospholipid bilayer and can be secreted by most types of cells. EVs deliver cargo from...
David Ojcius
Sep 12, 20241 min read
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Negative Regulatory NLRs Mitigate Inflammation via NF-κB Pathway in Inflammatory Bowel Disease
A subset of NLRs function to mitigate overzealous pro-inflammatory signaling produced by NF-κB activation. Under normal pathophysiologic...
David Ojcius
Jun 14, 20234 min read
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Fasting as key tone for COVID immunity
#SARSCoV2-induced #anorexia triggers systemic metabolic alterations. A new study shows that the ketone body β-hydroxybutyrate (BHB)...
David Ojcius
Oct 1, 20226 min read
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How your body clock drives your immune system
The body's internal clock affects the immune system in ways scientists in the burgeoning field of #circadian #immunology are beginning to...
David Ojcius
Jun 25, 20224 min read
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What triggers severe COVID? Infected immune cells hold clues
Two studies show that immune cells infected with #SARSCoV2 can stimulate a large inflammatory response via #inflammasome activation. In...
David Ojcius
Apr 6, 20224 min read
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Current Research in Microbial Sciences - Editorial Board
Co-editors-in-chief Miranda Hart and David Ojcius #openaccess #microbiology #immunology #microbes #environment Find entire editorial...
David Ojcius
Mar 5, 20221 min read
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How the Immune System Senses Danger: Immunology Researcher David Ojcius Explains
It’s no secret that we rely on our immune systems to fight off common infections. But what you might not know is that the immune system...
David Ojcius
Feb 5, 20221 min read
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Immunology Research Professor David Ojcius Explains the Effects of Aging on Our Immune System
If you feel like you’re slowing down a bit as you age, you’re not alone. Many of our systems (including our brain) tend to taper off as...
David Ojcius
Jan 30, 20221 min read
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David Ojcius -- on Lifelong Learning as a Researcher
#microbiology #LifelongLearning #education #research #biophysics #Pacific #immunology Interview at Thrive Global What do you love most...
David Ojcius
Dec 8, 20211 min read
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The role of endocytic trafficking in antigen T cell receptor activation
This review article summarizes the molecular mechanisms of T cell receptor (TCR) #endocytosis and recycling, both in steady state and...
David Ojcius
Oct 12, 20212 min read
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The Moderna vaccine makes more antibodies than Pfizer's. Does it matter?
#coronavirus #SARSCoV2 #immunity #immunology #COVID19 The Moderna vaccine makes more antibodies than Pfizer's. Does it matter? Antibodies...
David Ojcius
Sep 5, 20214 min read
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Prior exposure to common cold coronaviruses enhances immune response to SARS-CoV-2
Researchers show that cross-reactive CD4+ T cells found in people previously exposed to common cold coronaviruses enhance the body's...
David Ojcius
Sep 4, 20216 min read
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Scaling the tips of the ALPS
by Frédéric Rieux-Laucat, Jean M. Kanellopoulos, David M. Ojcius #apoptosis #immunology #FAS #autoimmunity This special issue contains...
David Ojcius
Aug 23, 20218 min read
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Human Blood Harbors Cell-Free Microbial DNA
After controlling for high levels of bacterial contamination in their lab and reagents, researchers detect microbial genetic material in...
David Ojcius
Jul 13, 20213 min read
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New impact factor for Biomedical Journal is now 4.91 !!
The new (2020) #impactfactor for Biomedical Journal is 4.91. The journal continues to improve. We thank all authors and editors for your...
David Ojcius
Jun 30, 20211 min read
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Purinergic signaling: a new front-line determinant of resistance and susceptibility in leishmaniasis
#immunology #innateimmunity #Leishmania Leishmaniasis is a neglected tropical disease that causes several clinical manifestations....
David Ojcius
Jun 24, 20211 min read
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The genetic landscape of the FAS pathway deficiencies
#genetics #autoimmunedisease #autoimmunity #immunology #apoptosis Dysfunction of the FAS-FASLG pathway causes a lymphoproliferative...
David Ojcius
Jun 24, 20211 min read
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Cause or effect? The spatial organization of pathogens and the gut microbiota in disease
#microbiota #microbiome #immunology #microbiology The human gut hosts a dense and diverse microbial community, spatially organized by...
David Ojcius
Jun 21, 20211 min read
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Multivalent antibodies show high potency against SARS-CoV-2 in new study
#SARSCoV2 #antibodies #immunology #coronavirus #COVID19 Since the beginning of the severe acute respiratory syndrome coronavirus 2...
David Ojcius
Jun 21, 20214 min read
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