Negative Regulatory NLRs Mitigate Inflammation via NF-κB Pathway in Inflammatory Bowel Disease
A subset of NLRs function to mitigate overzealous pro-inflammatory signaling produced by NF-κB activation. Under normal pathophysiologic...
Welcome to Mostly Microbes and Infectious Diseases. David Ojcius posts newspaper and journal articles in the broad field of microbiology.
A subset of NLRs function to mitigate overzealous pro-inflammatory signaling produced by NF-κB activation. Under normal pathophysiologic...
#SARSCoV2-induced #anorexia triggers systemic metabolic alterations. A new study shows that the ketone body β-hydroxybutyrate (BHB)...
The body's internal clock affects the immune system in ways scientists in the burgeoning field of #circadian #immunology are beginning to...
Two studies show that immune cells infected with #SARSCoV2 can stimulate a large inflammatory response via #inflammasome activation. In...
Co-editors-in-chief Miranda Hart and David Ojcius #openaccess #microbiology #immunology #microbes #environment Find entire editorial...
It’s no secret that we rely on our immune systems to fight off common infections. But what you might not know is that the immune system...
If you feel like you’re slowing down a bit as you age, you’re not alone. Many of our systems (including our brain) tend to taper off as...
#microbiology #LifelongLearning #education #research #biophysics #Pacific #immunology Interview at Thrive Global What do you love most...
This review article summarizes the molecular mechanisms of T cell receptor (TCR) #endocytosis and recycling, both in steady state and...
#coronavirus #SARSCoV2 #immunity #immunology #COVID19 The Moderna vaccine makes more antibodies than Pfizer's. Does it matter? Antibodies...
Researchers show that cross-reactive CD4+ T cells found in people previously exposed to common cold coronaviruses enhance the body's...
by Frédéric Rieux-Laucat, Jean M. Kanellopoulos, David M. Ojcius #apoptosis #immunology #FAS #autoimmunity This special issue contains...
After controlling for high levels of bacterial contamination in their lab and reagents, researchers detect microbial genetic material in...
The new (2020) #impactfactor for Biomedical Journal is 4.91. The journal continues to improve. We thank all authors and editors for your...
#immunology #innateimmunity #Leishmania Leishmaniasis is a neglected tropical disease that causes several clinical manifestations....
#genetics #autoimmunedisease #autoimmunity #immunology #apoptosis Dysfunction of the FAS-FASLG pathway causes a lymphoproliferative...
#microbiota #microbiome #immunology #microbiology The human gut hosts a dense and diverse microbial community, spatially organized by...
#SARSCoV2 #antibodies #immunology #coronavirus #COVID19 Since the beginning of the severe acute respiratory syndrome coronavirus 2...
#microbiology #pathogenesis #immunology #immunity #bacteria #virus #virology #mycology #infectiousdisease #genetics #microbiota The...
#immunology #Salmonella #vaccines #evolution #microbiology Researchers succeeded in developing an oral vaccine against Salmonella that...