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MOSTLY MICROBES AND INFECTIOUS DISEASES

Welcome to Mostly Microbes and Infectious Diseases. David Ojcius posts newspaper and journal articles in the broad field of microbiology.

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How to Get Rid of Bad Breath

Consider what you eat - but also get rid of oral bacteria that release volatile sulfur compounds by brushing & flossing. #halitosis #oralhealth Garlic and onions are two of my favorite foods — I have been known to eat roasted garlic cloves like candy — so it’s no surprise that I often find myself surreptitiously smelling my breath and wincing. Studies on the prevalence of bad breath are hard to come by, but research has estimated that up to half of all Americans have been c

Do oral bacteria play a role in hypertension?

Researchers found an association between the oral #microbiota and the risk of #hypertension in people who have experienced menopause. Specific bacteria were associated with both baseline blood pressure and the risk of developing hypertension. #oralhealth #heart #heartdisease #microbiology #microbiome Almost half of adults in the United States have high blood pressure, or hypertension. People with hypertension have an increased risk of stroke and heart disease. The researchers

Review on association of fungi with development and progression of carcinogenesis in the human body

Highlights •Long-term #Candida infection contributes to #oralcancer development. •Candida species contribute to tumor induction along the gastrointestinal tract through production of carcinogenic nitrosamines. •Voriconazole is involved in the development of squamous cell carcinoma in lung transplant patients. #cancer #mycobiota #microbiota #microbiome #oralhealth Abstract The role and impact of commensal and pathogenic fungi in different parts of the human body are being inc

David Ojcius Discusses The Association Between Oral Health And Systemic Disease

The association between #oralhealth and systemic disease has been established for some time. Medical research has pointed to a link between health conditions such as #diabetes and #cardiovascular disease and #periodontal disease. What’s still debatable though is how #oral bacteria can have such an impact on the oral cavity that it could lead to health conditions in other parts of the body. David Ojcius is the assistant dean of research and the chair of the Biomedical Sciences

Microbiote de la bouche

de Sylvie Babajko, David Ojcius, Ihsène Taihi-Nassif #microbiome #microbiota #oralhealth La cavité buccale est une partie du corps en interface directe et variable avec l’environnement. Organe de communication (phonation, mimiques, esthétique…), elle est aussi indispensable à de nombreuses fonctions vitales comme la circulation de l’air, la mastication, la salivation… Porte d’entrée des voies aériennes supérieures et du système digestif, elle joue un rôle important pour celui

Dental Care is Essential Care: The Importance of Getting Back on Track with Your Oral Healthcare

#dentalcare #oralhealth #dentistry #dental #pandemic #COVID19 Over the past year and a half, many of us have taken “business casual” to new lengths, working in sweatpants or pajamas and forgoing many of our usual self-care routines. While we lamented closed shops and salons, many of us also glossed over missed appointments with our physicians and —our dentists. The COVID-19 pandemic may have placed a spotlight on health, however physical restrictions resulted in missed dental

Effects of electronic cigarette aerosol exposure on oral and systemic health

Effects of electronic cigarette aerosol exposure on oral and systemic health #oralhealth #cigarettes #vaping #ecigarettes Conventional cigarette smoke harms nearly every organ of the body and is the leading cause of death in the United States and in the world. Decades of research have associated conventional cigarette smoke with several diseases and death. Heavily marketed, electronic nicotine delivery systems such as electronic cigarettes (e-cigarettes) are available in a va

Tooth Loss May Affect Ability to Carry Out Everyday Tasks

#oralhealth #teeth #tooth #dental #dentistry #dentist Summary: Older adults with more natural teeth are better able to carry out simple everyday tasks like cooking and cleaning compared to those who have lost their teeth, a new study reports. Researchers found a causal link between tooth loss and functional capacity in older adults. Tooth loss was also associated with a decline in social activity. The study published in the Journal of American Geriatrics Society, analysed dat

The Role of Medicine and Technology in Shaping the Future of Oral Health

by Namrata Nayyar, David Ojcius, Arthur Dugoni #oralhealth #dental #dentistry #technology #medicine #genomics #robotics #artificialintelligence #AI This commentary describes the changes taking place in dentistry and speculates on improvements that could happen soon. Advances in health care will have an impact on the integration and delivery of oral care; conversely, there is growing acceptance that oral health impacts systemic health. Technological innovations are changing th

Involvement of inflammasomes in immune response against infection by periodontal bacteria

by Kívia Queiroz De Andrade, Cássio Luiz Coutinho Almeida-da-Silva, David Ojcius, Robson Coutinho-Silva #inflammation #immunology #microbiology #oralhealth #dental #dentistry #periodontal #oral Differential involvement of the canonical and noncanonical inflammasomes in the immune response against infection by the periodontal bacteria Porphyromonas gingivalis and Fusobacterium nucleatum We examined the involvement of the P2 × 7 receptor and the canonical and noncanonical infla

Is there an association between oral health and severity of COVID-19 complications?

by Nathalie Botros, Parvati Iyer, David Ojcius #oralhealth #COVID19 #coronavirus #dental #dentistry Most patients with severe complications from COVID-19 have underlying conditions such as obesity, diabetes, and hypertension. In parallel, there is growing evidence for a link between periodontitis and non-oral systemic diseases. The oral cavity is also a reservoir for respiratory pathogens, and patients with periodontal disease are more likely to develop hospital-acquired pneu

David Ojcius Discusses The Association Between Oral Health And Systemic Disease

#oralhealth #microbiology #immunology The association between oral health and systemic disease has been established for some time. Medical research has pointed to a link between health conditions such as diabetes and cardiovascular disease and periodontal disease. What’s still debatable though is how oral bacteria can have such an impact on the oral cavity that it could lead to health conditions in other parts of the body. Read more at: https://www.trueactivist.com/david-ojci

Involvement of canonical and noncanonical inflammasomes in immune response against oral pathogens

#immunology #oralhealth #innateimmunity #inflammation #inflammasome #dental #dentistry We examined the involvement of the P2 × 7 receptor and the canonical and noncanonical inflammasomes in the control of single-species or dual-species infection by the periodontal bacteria Porphyromonas gingivalis and Fusobacterium nucleatum in cells and mice. Stimulation of the P2 × 7 receptor leads to activation of the canonical NLRP3 inflammasome and activation of caspase-1, which leads to

Nathalie Botros, Parvati Iyer, David Ojcius: Does oral health affect severity of COVID-19?

#COVID19 #coronavirus #oralhealth #dental #dentistry Most patients with severe complications from COVID-19 have underlying conditions such as obesity, diabetes, and hypertension. In parallel, there is growing evidence for a link between periodontitis and non-oral systemic diseases. The oral cavity is also a reservoir for respiratory pathogens, and patients with periodontal disease are more likely to develop hospital-acquired pneumonia than healthy individuals. We therefore hy

David Ojcius Discusses The Association Between Oral Health And Systemic Disease

The association between #oralhealth and systemic disease has been established for some time. Medical research has pointed to a link between health conditions such as diabetes and cardiovascular disease and periodontal disease. What’s still debatable though is how oral bacteria can have such an impact on the oral cavity that it could lead to health conditions in other parts of the body. David Ojcius is the assistant dean of research and the chair of the Biomedical Sciences dep

Association between periodontal pathogens and systemic disease

#oralhealth #inflammation #Alzheimers #pregnancy #pneumonia #obesity #diabetes #heartidisease A growing body of literature suggests that there is a link between periodontitis and systemic diseases. These diseases include cardiovascular disease, gastrointestinal and colorectal cancer, diabetes and insulin resistance, and Alzheimer's disease, as well as respiratory tract infection and adverse pregnancy outcomes. The presence of periodontal pathogens and their metabolic by-produ

Is there an association between oral health and severity of COVID-19 complications?

#COVID19 #coronavirus #oralhealth #dentistry Most patients with severe complications from COVID-19 have underlying conditions such as obesity, diabetes, and hypertension. In parallel, there is growing evidence for a link between periodontitis and non-oral systemic diseases. The oral cavity is also a reservoir for respiratory pathogens, and patients with periodontal disease are more likely to develop hospital-acquired pneumonia than healthy individuals. We therefore hypothesiz

Is there an association between oral health and severity of COVID-19 complications?

#COVID19 #coronavirus #oralhealth Most patients with severe complications from COVID-19 have underlying conditions such as obesity, diabetes, and hypertension. In parallel, there is growing evidence for a link between periodontitis and non-oral systemic diseases. The oral cavity is also a reservoir for respiratory pathogens, and patients with periodontal disease are more likely to develop hospital-acquired pneumonia than healthy individuals. We therefore hypothesize that impr

Need a New Tooth? Drug Discovered to Regenerate Lost Teeth

#oralhealth #dental #dentistry #dentist Need a New #Tooth? Drug Discovered to Regenerate Lost #Teeth A new study reports that an antibody for one gene (uterine sensitization associated gene-1 or USAG-1) can stimulate tooth growth in mice suffering from tooth agenesis, a congenital condition. https://scitechdaily.com/need-a-new-tooth-drug-discovered-to-regenerate-lost-teeth/

Involvement of inflammasomes in the immune response against infection by the periodontal bacteria

#immunology #inflammation #innateimmunity #oralhealth #dental #dentistry We examined the involvement of the P2 × 7 receptor and the canonical and noncanonical inflammasomes in the control of single-species or dual-species infection by the periodontal bacteria Porphyromonas gingivalis and Fusobacterium nucleatum in cells and mice. Stimulation of the P2 × 7 receptor leads to activation of the canonical NLRP3 inflammasome and activation of caspase-1, which leads to cleavage of p

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