Beta lactamase-producing Neisseria gonorrhoeae alleviates Amoxicillin-induced chlamydial persistence
Highlights • #Chlamydia trachomatis (CT) and $Neisseria gonorrhoeae (NG) co-infections are common. • N. gonorrhoeae may cause a...
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MOSTLY MICROBES AND INFECTIOUS DISEASES
Welcome to Mostly Microbes and Infectious Diseases. David Ojcius posts newspaper and journal articles in the broad field of microbiology.
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Probiotic supplements may do the opposite of boosting your gut health
In healthy people, #probiotic supplements offer little benefit & can potentially do more harm than good. Studies show that taking...
Mucin glycans drive oral microbial community composition & function
Study found mucins shape oral #microbiota by serving as nutrients to support metabolic diversity, organizing spatial structure thru...
How fit is your gut microbiome? New research shows duration and not intensity of exercise is most im
#exercise has many benefits—strengthening muscles and bones, preventing disease and extending lifespan. It is also known to change the...
Gut feelings: why drugs that nurture your microbes could be the future of mental health
Scientists know our gut influences our brain. So psychobiotic drugs that shift the composition of microbes in the gut may be able to help...
McGeorge School of Law secures $5 million to improve mental health services in California
University of the Pacific’s McGeorge School of Law is launching an innovative program to help local governments make transformative...
The role of NOD-like receptors in innate immunity
by Cassio Luiz Coutinho Almeida-da-Silva, Luiz Eduardo Baggio Savio, Robson Coutinho-Silva and David M. Ojcius The innate immune system...
A role for pore-forming proteins in the pathogenesis by parasites?
by David M. Ojcius, John Ding-E Young Over the past decade or so, pore-forming proteins (PFPs) have been isolated from various immune...
The CRISPR-associated Cas4 protein from Leptospira interrogans demonstrates nuclease activity
Highlights •LinCas4 is a metal dependent endonuclease. •Mutation of metal interacting residues (Asp74 and Glu87) curtails the DNase...
Transcriptome responses of intestinal epithelial cells induced by membrane vesicles of Listeria
Highlights •We report the transcriptome profiling of Caco-2 cells upon interaction with membrane vesicles of #Listeria monocytogenes....
3D culture models to study SARS-CoV-2 infectivity and antiviral candidates: From spheroids to biopri
The pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (#SARSCoV2) is receiving worldwide attention, due to the severity...
Arabidopsis nonhost resistance gene, IMPORTIN ALPHA 2 provides immunity against rice sheath blight
Highlights •Rice sheath blight is caused by necrotrophic dreadful fungus Rhizoctonia solani. •Forward genetics tools identified RSS1...
Characterization of the ompL1 gene of pathogenic Leptospira species in China
Background The usefulness of available vaccine and serological tests for leptospirosis is limited by the low cross-reactivity of antigens...
Effects of electronic cigarette aerosol exposure on oral and systemic health
by Cássio Luiz Coutinho Almeida-da-Silva , Harmony Matshik Dakafay , Kenji O'Brien , Dallin Montierth , Nan Xiao , David M Ojcius...
Don’t feel like exercising? It could be your microbiome
The microbiomes of physically active people can be quite different from those of people who rarely #exercise #microbiome #microbiota Your...
Association between Periodontal Disease and Cognitive Impairment in Adults
Najwane Said-Sadier, Batoul Sayegh, Raymond Farah, Linda Abou Abbas, Rania Dweik, Norina Tang and David M. Ojcius Introduction:...
X-ray projection imaging of metal oxide particles inside gingival tissues
Jarrod N. Cortez (1), Ignacio O. Romero (1), Md Sayed Tanveer (3), Chuang Niu (3), Cássio Luiz Coutinho Almeida-da-Silva (2), Leticia...
Did flu come from fish?
Researchers trawling genetic databases discovered a distant relative of #influenza viruses in sturgeon. The wider #flu virus family that...
Ivermectin Inhibits Growth of Chlamydia trachomatis in Epithelial Cells
by Matthew A. Pettengill,Verissa W. Lam,Ikechukwu Ollawa,Camila Marques-da-Silva,David M. Ojcius. #Ivermectin is currently approved for...
Interactions between silica and titanium nanoparticles and oral and gastrointestinal epithelia
by Cassio Luiz Coutinho Almeida-da-Silva, Leticia Ferreira Cabido, Wei-Chun Chin, Ge Wang, David M. Ojcius and Changqing Li. Engineered...
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