Clinical development of antivirals against SARS-CoV-2 and its variants
Abstract The unceasing global spread of severe acute respiratory syndrome #coronavirus 2 (#SARSCoV2) calls for the development of novel...
Welcome to Mostly Microbes and Infectious Diseases. David Ojcius posts newspaper and journal articles in the broad field of microbiology.
Abstract The unceasing global spread of severe acute respiratory syndrome #coronavirus 2 (#SARSCoV2) calls for the development of novel...
Large GWAS indicated that genetic factors influence the response to #SARSCoV2. However, sex, age, concomitant diseases, differences in...
#aging increases vulnerability to respiratory viral infections, including by #SARSCoV2. Delval et al. established a causal role for...
Coronaviruses, including #SARSCoV2, have caused pandemics in the past two decades. The most prevalent SARS-CoV-2 variants of concern can...
The pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (#SARSCoV2) is receiving worldwide attention, due to the severity...
Coronaviruses, including #SARSCoV2, have caused pandemics in the past two decades. The most prevalent SARS-CoV-2 variants of concern can...
#SARSCoV2-induced #anorexia triggers systemic metabolic alterations. A new study shows that the ketone body β-hydroxybutyrate (BHB)...
Just 10 months after the initial genome sequencing of the #SARSCoV2 virus, two mRNA vaccines were demonstrated to provide 95% efficacy...
Smell disruption from #COVID19 is becoming less-common, but millions of people still have problems with their sense of #smell. The...
A study found that people with food #allergies are less likely to become infected with the #SARSCoV2 #coronavirus. The study also found...
Two studies show that immune cells infected with #SARSCoV2 can stimulate a large inflammatory response via #inflammasome activation. In...
3 recent preprints offer further evidence supporting the hypothesis that the #coronavirus spread from animals to people. A next step in...
Even a mild case of #COVID19 can damage the brain, leading to shrinkage equivalent to up to a decade of #aging, according to a new study....
Scientists in Canada discovered the 1st potential case of deer passing #coronavirus to a human, according to a preprint. The discovery...
New York City’s #wastewater contains #coronavirus sequences with unique mutations that have not been reported in human patients. There...
#LongCovid symptoms less likely in vaccinated people, Israeli data say. People who have had both #SARSCoV2 #coronavirus infection &...
Evolution of enhanced innate immune evasion by the #SARSCoV2 #coronavirus. "Importance of mutations outside Spike in adaptation of...
by David Chambers, Michelle Brady, David Ojcius, Evelyn Cuny #COVID19 #COVID #SARSCoV2 #coronavirus #dentistry #dental 1 PROBLEM What...
In the effort to track the spread of #SARSCoV2 #coronavirus, researchers are monitoring #wastewater in many locations around the state of...
A new study (not peer-reviewed yet) shows evidence that the #SARSCoV2 #coronavirus spreads widely in white-tailed deer, & the virus is...