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MOSTLY MICROBES AND INFECTIOUS DISEASES
Welcome to Mostly Microbes and Infectious Diseases. David Ojcius posts newspaper and journal articles in the broad field of microbiology.
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The oral microbiota: living with a permanent guest
by Maria Avila, David M Ojcius, Ozlem Yilmaz. The oral cavity of healthy individuals contains hundreds of different bacterial, viral, and...
David Ojcius
May 13, 20231 min read
Infection of the oral cavity with SARS-CoV-2 variants: Scope of salivary diagnostics
Coronaviruses, including #SARSCoV2, have caused pandemics in the past two decades. The most prevalent SARS-CoV-2 variants of concern can...
David Ojcius
May 7, 20232 min read
David Ojcius Discusses The Association Between Oral Health And Systemic Disease
David Ojcius is the assistant dean of research and the chair of the Biomedical Sciences department at the University of the Pacific....
David Ojcius
May 6, 20231 min read
Dicer regulates activation of the NLRP3 inflammasome
by David M. Ojcius, Ardavan Jafari, Laxmi Yeruva, Christian W. Schindler, Ali A. Abdul-Sater Inflammation plays a critical role in...
David Ojcius
Apr 30, 20231 min read
What SuperAgers show us about longevity, cognitive health as we age
· Eat like a centenarian by incorporating fiber-rich foods into your diet. · Exercise your body. · #Exercise your brain. · Stay...
David Ojcius
Apr 13, 20232 min read
Longevity of centenarians is reflected by the gut microbiome with youth-associated signatures
Centenarians display youth-associated features in gut #microbiome such as over-representation of #Bacteroides-dominated enterotype,...
David Ojcius
Apr 12, 20233 min read
Intermittent fasting modulates gut microbiota and improves obesity and host energy metabolism
A small study in humans found that #IntermittentFasting modulates the intestinal #microbiota & improves #obesity & host energy...
David Ojcius
Apr 8, 20233 min read
Beta lactamase-producing Neisseria gonorrhoeae alleviates Amoxicillin-induced chlamydial persistence
Highlights • #Chlamydia trachomatis (CT) and $Neisseria gonorrhoeae (NG) co-infections are common. • N. gonorrhoeae may cause a...
David Ojcius
Mar 30, 20235 min read
Probiotic supplements may do the opposite of boosting your gut health
In healthy people, #probiotic supplements offer little benefit & can potentially do more harm than good. Studies show that taking...
David Ojcius
Mar 28, 20235 min read
Mucin glycans drive oral microbial community composition & function
Study found mucins shape oral #microbiota by serving as nutrients to support metabolic diversity, organizing spatial structure thru...
David Ojcius
Mar 26, 20232 min read
How fit is your gut microbiome? New research shows duration and not intensity of exercise is most im
#exercise has many benefits—strengthening muscles and bones, preventing disease and extending lifespan. It is also known to change the...
David Ojcius
Mar 23, 20232 min read
Gut feelings: why drugs that nurture your microbes could be the future of mental health
Scientists know our gut influences our brain. So psychobiotic drugs that shift the composition of microbes in the gut may be able to help...
David Ojcius
Mar 21, 20233 min read
McGeorge School of Law secures $5 million to improve mental health services in California
University of the Pacific’s McGeorge School of Law is launching an innovative program to help local governments make transformative...
David Ojcius
Mar 20, 20233 min read
The role of NOD-like receptors in innate immunity
by Cassio Luiz Coutinho Almeida-da-Silva, Luiz Eduardo Baggio Savio, Robson Coutinho-Silva and David M. Ojcius The innate immune system...
David Ojcius
Mar 15, 20232 min read
A role for pore-forming proteins in the pathogenesis by parasites?
by David M. Ojcius, John Ding-E Young Over the past decade or so, pore-forming proteins (PFPs) have been isolated from various immune...
David Ojcius
Mar 15, 20231 min read
The CRISPR-associated Cas4 protein from Leptospira interrogans demonstrates nuclease activity
Highlights •LinCas4 is a metal dependent endonuclease. •Mutation of metal interacting residues (Asp74 and Glu87) curtails the DNase...
David Ojcius
Mar 14, 20231 min read
Transcriptome responses of intestinal epithelial cells induced by membrane vesicles of Listeria
Highlights •We report the transcriptome profiling of Caco-2 cells upon interaction with membrane vesicles of #Listeria monocytogenes....
David Ojcius
Mar 13, 20232 min read
3D culture models to study SARS-CoV-2 infectivity and antiviral candidates: From spheroids to biopri
The pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (#SARSCoV2) is receiving worldwide attention, due to the severity...
David Ojcius
Mar 12, 20231 min read
Arabidopsis nonhost resistance gene, IMPORTIN ALPHA 2 provides immunity against rice sheath blight
Highlights •Rice sheath blight is caused by necrotrophic dreadful fungus Rhizoctonia solani. •Forward genetics tools identified RSS1...
David Ojcius
Mar 12, 20231 min read
Characterization of the ompL1 gene of pathogenic Leptospira species in China
Background The usefulness of available vaccine and serological tests for leptospirosis is limited by the low cross-reactivity of antigens...
David Ojcius
Mar 12, 20231 min read
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