N-Acetylglucosamine Enhances Anti-Anthracnose Metabolite Production in Actinokineospora bangkokensis Through Multi-Omics Analysis
A multi-omics analysis of Actinokineospora bangkokensis 44EHWT showed that N-acetylglucosamine acts as a pathway-specific regulator rather than a universal activator of biosynthetic gene clusters. Metabolomic profiling detected 493 induced features and enrichment of cyclic peptides and polyketides, while transcriptomic data revealed complex regulation underlying increased bioactive metabolite production.
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