Gut barrier disruption and chronic disease
Highlights Maintenance of gut barrier integrity is indispensable for health as the #gut barrier protects the host against gut microbes, food antigens, and toxins. Many factors such as enteric #infection, #antibiotics, low-fiber diets, #circadian rhythm disruption, and psychological #stress can affect gut barrier integrity and lead to systemic, low-grade #inflammation due to translocation of bacteria and their components. While the body can resist transient gut barrier disrupt