Taurine deficiency as a driver of aging
Studying various animals, a study found that the amount of the semi-essential amino acid #taurine in circulation decreased with age....
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MOSTLY MICROBES AND INFECTIOUS DISEASES
Welcome to Mostly Microbes and Infectious Diseases. David Ojcius posts newspaper and journal articles in the broad field of microbiology.
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A Drug to Treat Aging May Not Be a Pipe Dream
New approaches to the biology of #senescence can make lives longer and healthier. #aging #senolytics LIFE EXPECTANCY IN the...
Senolytics reduce coronavirus-related mortality in old mice
#senescence #COVID19 #coronavirus #aging #inflammation Targeting senescent cells using senolytic drugs before or after coronavirus...
The first non-invasive biomarker to track and verify efficacy of senolytic drugs
#senescence #aging Researchers have discovered a novel, non-invasive biomarker (15-deoxy-delta-12, 14-prostaglandin J2; dihomo-15d-PGJ2)...
Targeting metabolism to influence aging
Glutamine has a host of metabolic functions, including biosynthesis, redox maintenance, and chromatin biology. Drugs are currently...
Scientists develop new gene therapy strategy to delay aging
Researchers conducted genome-wide #CRISPR-based screens in premature aging stem cells & identified >100 candidate #senescence-promoting...
Effects of Aging on Our Immune System
If you feel like you’re slowing down a bit as you age, you’re not alone. Many of our systems (including our brain) tend to taper off as...
NAD boosting to reverse senescence and inflammaging.
Senescent cells promote NAD tissue decline during aging through CD38 enzymes which can now become a novel therapeutic target....
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