Senescence: No country for old cells
by Jan Martel, David M. Ojcius and John D. Young 1. Introduction Human health requires homeostasis and coherence to respond to stress and...
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MOSTLY MICROBES AND INFECTIOUS DISEASES
Welcome to Mostly Microbes and Infectious Diseases. David Ojcius posts newspaper and journal articles in the broad field of microbiology.
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Santé et Pauvreté dans les Pays du Sud
Ce numéro spécial apporte des éléments de réflexion sur l’accès à la santé dans les pays du Sud. Un premier chapitre est consacré à...
Life extension
Life extension is the concept of extending the human lifespan, either modestly through improvements in medicine or dramatically by...
Multiple energy X-ray imaging of metal oxide particles inside gingival tissues
by Jarrod Cortez , Ignacio Romero , Jason Ngo , Md Sayed Tanveer Azam , Chuang Niu , Cássio Luiz Coutinho Almeida-da-Silva , Leticia...
Lifestyle interventions to delay senescence
by Jan Martel, David M. Ojcius, John D. Young. #senescence is a condition of cell cycle arrest that increases #inflammation and...
University of the Pacific Office of Research and Sponsored Programs
Assistant Provost for Research: David Ojcius. The Office of Research and Sponsored Programs strives to provide the highest quality of...
Calorie restriction in humans builds strong muscle & stimulates healthy aging genes
#CalorieRestriction is known to delay progression of age-related diseases in animal models. A new study suggests the same biological...
Scientists Use CRISPR to Make Chickens More Resistant to Bird Flu
Scientists have used #CRISPR to create chickens that have some resistance to #avianflu. The research is "proof of concept that we can...
Urbanization associates with restricted gut microbiome diversity and delayed maturation in infants
Urbanization associates with restricted gut #microbiome diversity & delayed maturation in infants in Senegal. •Urban infants also more...
Gut barrier disruption and chronic disease
by Jan Martel, Shih-Hsin Chang, Yun-Fei Ko, Tsong-Long Hwang, John D. Young & David M. Ojcius Maintenance of gut barrier integrity is...
Jorvik: a membrane-containing phage that will likely found a new family within Vinavirales
Study identifies a new type of membrane-containing #bacteriophage, Jorvik, that infects the freshwater mixotrophic model bacterium...
Your microbes live on after you die − how your necrobiome recycles your body to nourish new life
How your #necrobiome recycles your body to nourish new life. Studies show that not only do our microbes continue to live on after we die,...
How climate change could make fungal diseases worse
Fungal diseases in general are appearing in places they have never been seen before & previously harmless or mildly harmful #fungi are...
Pacific has one of most successful years for grants in school history
University of the Pacific secured 62 grants from federal, state and county agencies totaling more than $36 million—one of the best years...
Inflammasome-mediated glucose limitation induces antibiotic tolerance in Staphylococcus aureus
• #Staphylococcus aureus activates #NLRP3 #inflammasome in macrophages • NLRP3 activation --> depletion of glucose in macrophage...
The oral microbiome: diversity, biogeography and human health
Review article highlights recent understanding of biogeography of oral niches at the species level & summarizes the relationship between...
More reasons to eat mushrooms & fried crickets!
Study in mice found that digesting #chitin, an abundant dietary fiber in insect exoskeletons & mushrooms & crustacean shells, engages the...
A GWAS in the pandemic epicenter highlights severe COVID-19 risk locus introgressed by Neanderthals
Large GWAS indicated that genetic factors influence the response to #SARSCoV2. However, sex, age, concomitant diseases, differences in...
How a simple mouth rinse may be able to predict heart disease risk
Study shows that a simple mouth rinse that checks white blood cell levels may be helpful in predicting #heart disease. The rinse can...
Chlamydia and apoptosis: life and death decisions of an intracellular pathogen
The chlamydiae are important obligate intracellular prokaryotic pathogens that, each year, are responsible for millions of human...
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