In‑cell structural mapping of bacterial translation uncovers a transcription‑translation‑membrane supercomplex

Using cryo‑electron tomography, researchers resolve 140 structures from Mycoplasma pneumoniae that depict translation across all major phases. They visualize transcription‑translation complexes, propose a reinitiation mechanism, and uncover structural evidence for a supercomplex linking transcription, translation, and membrane attachment. Membrane‑associated large subunits suggest conserved regulatory dynamics.

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