Jean Kanellopoulos and David Ojcius: Neither B cell nor T cell – the innate lymphoid cells

#immunology #innateimmunity #ILC

This free special issue contains four review articles that analyze the development and biology of innate lymphoid cells (ILCs), which are the most recently-discovered group of innate immune cells. This unique group of lymphoid cells lacks the RAG gene and consequently does not express B cell nor T cell antigen-specific receptors. They are abundant at mucosal surfaces, where they play a role in immunity and homeostasis. The ILCs are the focus of intensive research efforts to understand their development and function.

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https://www.sciencedirect.com/science/article/pii/S2319417021000329