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MOSTLY MICROBES AND INFECTIOUS DISEASES
Welcome to Mostly Microbes and Infectious Diseases. David Ojcius posts newspaper and journal articles in the broad field of microbiology.

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McGeorge School of Law secures $5 million to improve mental health services in California
University of the Pacific’s McGeorge School of Law is launching an innovative program to help local governments make transformative...
David Ojcius
Mar 20, 20233 min read


The role of NOD-like receptors in innate immunity
by Cassio Luiz Coutinho Almeida-da-Silva, Luiz Eduardo Baggio Savio, Robson Coutinho-Silva and David M. Ojcius The innate immune system...
David Ojcius
Mar 15, 20232 min read


A role for pore-forming proteins in the pathogenesis by parasites?
by David M. Ojcius, John Ding-E Young Over the past decade or so, pore-forming proteins (PFPs) have been isolated from various immune...
David Ojcius
Mar 15, 20231 min read


The CRISPR-associated Cas4 protein from Leptospira interrogans demonstrates nuclease activity
Highlights •LinCas4 is a metal dependent endonuclease. •Mutation of metal interacting residues (Asp74 and Glu87) curtails the DNase...
David Ojcius
Mar 14, 20231 min read


Transcriptome responses of intestinal epithelial cells induced by membrane vesicles of Listeria
Highlights •We report the transcriptome profiling of Caco-2 cells upon interaction with membrane vesicles of #Listeria monocytogenes....
David Ojcius
Mar 13, 20232 min read


3D culture models to study SARS-CoV-2 infectivity and antiviral candidates: From spheroids to biopri
The pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (#SARSCoV2) is receiving worldwide attention, due to the severity...
David Ojcius
Mar 12, 20231 min read


Arabidopsis nonhost resistance gene, IMPORTIN ALPHA 2 provides immunity against rice sheath blight
Highlights •Rice sheath blight is caused by necrotrophic dreadful fungus Rhizoctonia solani. •Forward genetics tools identified RSS1...
David Ojcius
Mar 12, 20231 min read
Characterization of the ompL1 gene of pathogenic Leptospira species in China
Background The usefulness of available vaccine and serological tests for leptospirosis is limited by the low cross-reactivity of antigens...
David Ojcius
Mar 12, 20231 min read


Effects of electronic cigarette aerosol exposure on oral and systemic health
by Cássio Luiz Coutinho Almeida-da-Silva , Harmony Matshik Dakafay , Kenji O'Brien , Dallin Montierth , Nan Xiao , David M Ojcius...
David Ojcius
Mar 11, 20231 min read


Don’t feel like exercising? It could be your microbiome
The microbiomes of physically active people can be quite different from those of people who rarely #exercise #microbiome #microbiota Your...
David Ojcius
Mar 8, 20234 min read


Association between Periodontal Disease and Cognitive Impairment in Adults
Najwane Said-Sadier, Batoul Sayegh, Raymond Farah, Linda Abou Abbas, Rania Dweik, Norina Tang and David M. Ojcius Introduction:...
David Ojcius
Mar 7, 20234 min read


X-ray projection imaging of metal oxide particles inside gingival tissues
Jarrod N. Cortez (1), Ignacio O. Romero (1), Md Sayed Tanveer (3), Chuang Niu (3), Cássio Luiz Coutinho Almeida-da-Silva (2), Leticia...
David Ojcius
Mar 2, 20232 min read


Did flu come from fish?
Researchers trawling genetic databases discovered a distant relative of #influenza viruses in sturgeon. The wider #flu virus family that...
David Ojcius
Mar 1, 20233 min read


Ivermectin Inhibits Growth of Chlamydia trachomatis in Epithelial Cells
by Matthew A. Pettengill,Verissa W. Lam,Ikechukwu Ollawa,Camila Marques-da-Silva,David M. Ojcius. #Ivermectin is currently approved for...
David Ojcius
Feb 26, 20232 min read


Interactions between silica and titanium nanoparticles and oral and gastrointestinal epithelia
by Cassio Luiz Coutinho Almeida-da-Silva, Leticia Ferreira Cabido, Wei-Chun Chin, Ge Wang, David M. Ojcius and Changqing Li. Engineered...
David Ojcius
Feb 25, 20238 min read


An end to the H5N1 saga?
Ojcius, David. "An end to the H5N1 saga?" Nature Reviews Microbiology, vol. 10, no. 6, June 2012, p. 380. In recent weeks the debate over...
David Ojcius
Feb 25, 20231 min read


Stories by David M. Ojcius, Toni Darville and Patrik M. Bavoil
News and research about Stories by David M. Ojcius, Toni Darville and Patrik M. Bavoil, including commentary and archival articles...
David Ojcius
Feb 20, 20231 min read


How do pandemics begin? There's a new theory — and a new strategy to thwart them
Most new pathogens, up to 75%, come from animals. They're often viruses that have been circulating in animals for decades, even...
David Ojcius
Feb 18, 20234 min read


Is a return to nature a piece of the health puzzle?
In 1896, a German bookseller and self-educated man named Adolf Just founded the Jungborn sanatorium to promote a natural healing approach...
David Ojcius
Feb 15, 20231 min read


Towards multiomic analysis of oral mucosal pathologies
Oral mucosal pathologies comprise an array of diseases with worldwide prevalence and medical relevance. Affecting a confined space with...
David Ojcius
Feb 15, 20233 min read
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