Research suggests that chronic #viral infections have a profound & lasting impact on the human immune system in ways that are similar to those seen during #aging.
Using systems #immunology and #artificialintelligence, researchers profiled and compared immune responses in a cohort of aging individuals, people with HIV on long-term anti-retroviral therapy, and people infected with hepatitis C (HCV) before and after the virus was treated with a drug that has up to a 97% cure rate. Shared alterations in the immune system include T cell memory inflation, upregulation of intracellular signaling pathways of inflammation, and diminished sensitivity to cytokines in lymphocytes and myeloid cells.
https://medicalxpress.com/news/2021-03-chronic-viral-infections-effects-human.html